Endometriosis

Ovarian cancer risk is increased in women with endometriosis. Contraceptive use for 5 or more years reduces this risk. Danazol may increase ovarian cancer risk.
All use of hormonal therapies for endometriosis have side effects and put women’s health in danger. Some of them have more unpleasant side effects. Before taking medications or hormone therapy the possible adverse effects should be reviewed. If they are less unpleasant than the symptoms of endometriosis, hormone therapy should be discussed with your doctor.

GnRH and increased doses of progesterone can cause bone demineralization. Side effects of GnRH administration’s cause of low-dose hormone or combination with other drugs, and use only 6 months of GnRH. The effects of high dose progesterone on bones is low, it is required a therapy for 2 years to cause problems to the bone. After this therapy, bone density returns to normal in the majority or entirety.
It turned out in some studies on infertile women with severe endometriosis who are in therapy for 6 months with GnRH before in vitro fertilization that they had increased chances of conceiving a pregnancy.
Some studies show that use of GnRH therapy after surgery can extend painless periods, prevent proliferation and restoration of endometriosis.